Multinucleate sphere unknown (MSX)
Disease caused by Haplosporidium nelsoni

Haplosporidium nelsoni causes multinucleate sphere unknown (MSX) in cultured and wild American and Pacific cupped oysters. It is a reportable disease in Canada and suspected cases must be immediately reported to the CFIA.

The disease prevents oysters from thriving and can result in decreased rates of growth and increased oyster mortality.

MSX is not a food safety concern.

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Latest situation in PEI

We are responding to the presence of MSX in oysters collected in Prince Edward Island (PEI).

Movement control map for MSX

To prevent the spread of MSX in Canada, the CFIA has established primary control zones (PCZs) in the areas where the disease has been detected or is suspected to exist.

Permits are required for the movement of animals and things through a primary control zone.

Guidance on how to prevent the spread of MSX from PCZs to other locations within Canada is available on the MSX biosecurity guidelines for PCZs page.

Last updated: 2024-10-31

Haplosporidium nelsoni (MSX) Regulated Areas

Permits and conditions for movement controls

Movements of animals and things that are considered high risk of being infected with or contaminated by MSX require a permit to move into, within or out of the PCZ. You must apply for a permit from the CFIA before you are allowed to make the movement.

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For all permits listed, *things mean gear and equipment used in the fishing, harvest, or culture of oysters or spat, as well as materials that have been in contact with oysters or their spat, both wild and cultured, alive or dead and any parts thereof.

Prohibited movements

The movement of oysters or their spat both wild and cultured, alive or dead and any parts thereof out of a PCZ to a non-PCZ area (free area) for culture, relay, depuration or release into natural waterways is strictly prohibited.

What does your movement involve?

  • moving oysters or their spat, both wild and cultured, alive or dead, and any parts thereof, or things* into or within the PCZ
  • taking any gear or equipment used in the fishing, harvest or culture of oysters or their spat out of the PCZ
  • moving oysters after processing for human consumption, wholesale or retail within or out of the PCZ
  • taking oysters or their spat (whether wild, cultured, alive or dead or any parts thereof) out of a PCZ for processing, diagnostic and other testing or research
  • moving oysters or their spat from one PCZ to another PCZ

You will need General Permit 1

Any movement of oysters or their spat, both wild and cultured, alive or dead, and any parts thereof, or things* into or within a PCZ requires General Permit 1. All movements must meet the conditions listed in the permit.

Download and complete: General Permit 1

You will need General Permit 3

Movement of any gear or equipment associated, or having contact with of oysters or their spat, both wild and cultured, alive or dead and any parts thereof out of a PCZ requires General Permit 3. All movements must meet the conditions listed in the permit.

Download and complete: General Permit 3

You will need General Permit 4

Any movement of oysters from a processing facility for the purpose of direct to human consumption, wholesale or retail, out of, or within a PCZ requires General Permit 4. All movements must meet the conditions listed in the permit.

Download and complete: General Permit 4

You will need a specific permit

A specific permit is required for oysters or their spat, both wild and cultured, alive or dead and any parts thereof to be moved OUT of the PCZ for processing in a different PCZ, diagnostic and other testing, or research or OUT of one PCZ and INTO a different PCZ.

Download and complete: Request for a Specific Permit

Contact us

For questions related to permits and movement control permissions in PCZs, contact the CFIA support line: 1-902-370-1368.

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