Current status: Closed
This consultation ran from July 9, 2025 to August 8, 2025
About the consultation
We were seeking comments on the following amended single ingredient feed (SIF) descriptions:
- L-lysine
- L-lysine monohydrochloride
- L-lysine solution
Background
The Feeds Regulations, 2024 require a proponent to submit a pre-market application for new feed ingredients or SIFs that have been modified such that they differ from an approved SIF or SIFs that are for a new purpose. We evaluate the information in the application to establish that the SIF is safe, effective and labelled correctly.
Approved SIFs are listed and described in the Canadian Feed Ingredients Table (CFIT), which is incorporated by reference (IBR) into the Feeds Regulations, 2024. Our Incorporation by Reference Policy requires that a consultation be conducted before changes to IBR documents are made. Refer to Documents incorporated by reference under the Feeds Regulations, 2024 for additional information.
About the evaluation
Our Animal Feed Program (AFP) has identified that the current descriptions for L-lysine, L-lysine monohydrochloride and L-lysine solution do not have the correct nomenclature and therefore the existing descriptions are to be amended with the correct chemical name.
We recommend that the descriptions for L-lysine, L-lysine monohydrochloride and L-lysine solution be amended to reflect the current chemical name and the amended SIF descriptions replace the current SIF descriptions in the CFIT accordingly.
Amended SIF descriptions
We intend to amend the existing SIF description for L-lysine (1-501-003) under subclass 5.1.2 (Amino acids excluding those from fermentation processes) of class 5 (Nutritional ingredients) in part 1 of the CFIT. The description is to be amended to include the correct chemical name and to add the correct chemical name as an alternative name.
The amended description is:
L-Lysine (or (2S)-2,6-diaminohexanoic acid)
is the product that contains a minimum of 95% (2S)-2,6-diaminohexanoic acid and having the CAS# 56-87-1.
It shall be labelled with a guarantee for minimum percent L-lysine.
We also intend to amend the existing SIF description for L-lysine monohydrochloride (1-501-016) under subclass 5.1.2 (Amino acids excluding those from fermentation processes) of class 5 (Nutritional ingredients) in part 1 of the CFIT. The description is to be amended to include the correct chemical name and to add the correct chemical name as an alternative name. In addition, the description is to be amended to add a required label guarantee for L-lysine monohydrochloride to align with the required label guarantees for the new proposed SIF, L-lysine monohydrochloride from fermentation process.
The amended description is:
L-Lysine monohydrochloride (or (2S)-2,6-diaminohexanoic acid hydrochloride)
is the product that contains a minimum of 95% (2S)-2,6-diaminohexanoic acid hydrochloride (CAS# 657-27-2), with a maximum of 80% L-lysine (CAS# 56-87-1)
It shall be labelled with guarantees for minimum percent L-lysine monohydrochloride and minimum percent L-lysine.
In addition, we intend to amend the existing SIF description for L-lysine solution (1-501-017) under subclass 5.1.2 (Amino acids excluding those from fermentation processes) of class 5 (Nutritional ingredients) in part 1 of the CFIT. The description is to be amended to include the correct chemical name and to add the correct chemical name as another alternative name.
The amended description is:
L-Lysine solution (or liquid L-lysine or (2S)-2,6-diaminohexanoic acid solution)
is the product that contains a minimum of 50% (w/v) (2S)-2,6-diaminohexanoic acid in a water solution and having the CAS# 56-87-1.
It shall be labelled with a guarantee for minimum percent L-lysine.
Additional information
During the drafting of the description for L-lysine monohydrochloride from fermentation process, our AFP identified that the chemical name in the existing descriptions for L-lysine (1-501-003), L-lysine monohydrochloride (1-501-016) and L-lysine solution (1-501-017) were outdated. These existing descriptions use the chemical name alpha epsilon-diaminocaproic acid. This will be amended to (2S)-2,6-diaminohexanoic acid in these existing descriptions. The amendment to these existing descriptions is just an update to the name to reflect current naming conventions and does not change the SIF or its intended purpose.
In addition, other changes were made to the L-lysine monohydrochloride description to align with the new proposed description of L-lysine monohydrochloride from fermentation process, which included an additional label guarantee for L-lysine monohydrochloride.
The purpose of these SIFs is still as a supplemental source of the amino acid, L-lysine, for all livestock species.
Who was the focus of this consultation
Animal feed stakeholders, including:
- suppliers of feed ingredients
- commercial feed manufacturers
- feed importers, distributors and retailers
- industry associations
- other government departments
- international trading partners
- veterinarians
All comments were welcome from industry, governments, the public or other organizations or individuals.
Next steps
We will review all of the comments received. If no significant scientifically valid concerns are raised, we will finalize the amended descriptions for L-lysine, L-lysine monohydrochloride and L-lysine solution.
If significant concerns are raised, we will evaluate the additional information. A what we heard report that summarizes the feedback received will be published.
These amended SIF descriptions will be added to the CFIT at the next update.
Related information
Contact us
Animal Feed Program (AFP)
Canadian Food Inspection Agency
59 Camelot Dr
Ottawa ON K1A 0Y9
Email: cfia.afp-paa.acia@inspection.gc.ca