Guide to submitting applications for registration under the Fertilizers Act
Appendices
Appendix 1: List of mandatory tabs and sub-tabs
Figure 1: Format of the submission. All Tabs are mandatory and omitting any Tabs will result in the application for registration being rejected / returned to applicant during the first response stage. Please adhere to the headings of each tab as identified in the guide.
Appendix 2: Product ingredients and associated safety data requirements
Safety data requirements vary depending on the nature of the product and its risk profile. The presence of an active or inert ingredient in the product may trigger additional safety requirements. The following table details a number of common product ingredients and the associated safety data requirements. Note that all products comprising or containing industrial by-products or recycled organic materials require Tab 4 (Results of analysis).
Tabs 1, 2, 3 | Tab 4 - Metals | Tab 4 - Dioxins Furans | Tab 4 - Indicator Organisms | Tab 5 | |
---|---|---|---|---|---|
Indole-3-butyric acid (IBA) at a concentration not exceeding 1% of the product excluding products for spray application | Check | ||||
VAMs (Vesicular Arbuscular Myccorhizae) provided the species is substantially equivalent/representative of VAM group | Check | ||||
Rhizobia (species of the genera Rhizobium, Bradyrhizobium, Mesorhizobium and Sinorhizobium) provided the species is substantially equivalent/representative of the rhizobia group, and is not genetically modified. | Check | ||||
Bacillus subtilis provided the strain is representative of the species, is not genetically modified and does not produce any human enterotoxin. | Check |
Tabs 1, 2, 3 | Tab 4 - Metals | Tab 4 - Dioxins Furans | Tab 4 - Indicator Organisms | Tab 5 | |
---|---|---|---|---|---|
Mineral derived nutrients | Check | Check | source dependent | ||
Micronutrients | Check | Check | source dependent | ||
Plant extracts and residues | Check | Check | Check | ||
Seaweed | Check | Check | Check | ||
Fertilizers containing Cement by-products | Check | Check Table Note b | Check | ||
Fertilizers containing Compost | Check | Check | Check | ||
Fertilizers containing Meals | Check | Check | Check | ||
Fertilizers containing Processed sewage including composts thereof | Check | Check | Check | Check | |
Fertilizers containing Pulp and paper sludge | Check | Check | Check | Check | |
Fertilizers containing Wood ash | Check | Check | Check | ||
Fertilizers containing Organic waste | Check | Check | Check | ||
Silica | Check | Check | |||
Fish fertilizer | Check | Check | Check | ||
Biochar | Check | Check |
Table Note
- Table note b
-
require Thallium and Vanadium testing in addition to analysis of the 11 standard metals.
Tabs 1, 2, 3 | Tab 4 - Metals | Tab 4 - Dioxins Furans | Tab 4 - Indicator Organisms | Tab 5 | |
---|---|---|---|---|---|
Polymer coated fertilizers | Check | Check | |||
Polymeric soil stabilizers | Check | Check | |||
Wetting agents and surfactants | Check | Check | |||
Nano-encapsulated fertilizers and nano-materials Table Note c | Check | Check | |||
Plant growth regulators and Plant signalling compounds (for example Gibberellin, Cytokines, NAA, LCOs, Salicylic Acid, Chitosan, Hesperetin, Naringenin) other than Level I IBA as described above | Check | Check | |||
Registrable supplement(s) that would themselves require a full safety data package, blended with fertilizer. | Check | ingredient dependent | ingredient dependent | ingredient dependent | Check |
Viable microorganism(s) other than those described in Level I | Check | Check | Check | ||
Metabolites of organism(s) | Check | Check | Check |
Table Note
- Table Note c
-
All products in part or in whole comprised of nano-materials require full safety assessment.
Note: this does not constitute a comprehensive list of product /ingredient - specific requirements.
Appendix 3: Metals, dioxins/furans standards and maximum acceptable level of indicator organisms in fertilizers and supplements
Metals Standards
The metals of concern include arsenic (As), cadmium (Cd), chromium (Cr), cobalt (Co), copper (Cu), mercury (Hg), molybdenum (Mo), nickel (Ni), lead (Pb), selenium (Se) and zinc (Zn). Accumulation of these metals in soil over the long term may lead to plant, animal, environmental or human toxicity. The maximum concentration of metals permitted in a product depends on the application rate of the product.
Metals standards are predicated on the maximum acceptable cumulative addition to soils over a 45 year time period, as opposed to the actual concentration of the metal in the product. The application rate of a product is a crucial element in determining acceptable product metal concentrations. The 45 year cumulative application approach is intended to account for the persistence of metals in the environment which ultimately determines the level of contamination and thus, long term impacts.
The maximum acceptable product metal concentration (in mg metal/kg product) is calculated for each metal using the CFIA standards for maximum acceptable 45-year cumulative metal additions to soil (identified in Table 3) and the product's maximum recommended annual application rate as follows:
All fertilizers and supplements, including processed sewage, composts and other by-products are required to meet the standards for maximum acceptable cumulative metal additions to soil.
Certain metals such as copper (Cu), molybdenum (Mo) and zinc (Zn) are also essential plant nutrients. Products represented to contain (for example guarantee) Cu, Mo or Zn that are used to treat a specific nutrient deficiency are not required to have an application rate specified on the label; rather the label states that the application rate is to be based on a soil or tissue test. In those instances, concentrations of the metal may exceed the metal standard (due to limited frequency of application) and the 95th percentile of the provincially recommended agronomic application rate is used in the calculations. These products must still meet the prescribed labelling standards including representation of the element as a plant nutrient, the associated guaranteed analysis and appropriate precautionary statements. Table 5 shows the acceptable metals concentrations for products at different application rates.
Metal | Maximum acceptable cumulative metal addition to soil over 45 years (kg metal/ha) |
Examples of maximum acceptable concentration of a metal based on annual application rate
(mg metal/kg product) 4400 kg/ha - yr |
Examples of maximum acceptable concentration of a metal based on annual application rate (mg metal/kg product) 2000 kg/ha - yr |
Examples of maximum acceptable concentration of a metal based on annual application rate (mg metal/kg product) 500 kg/ha - yr |
---|---|---|---|---|
Arsenic (As) | 15 | 75 | 166 | 666 |
Cadmium (Cd) | 4 | 20 | 44 | 177 |
Chromium (Cr) | 210 | 1060 | 2333 | 9333 |
Cobalt (Co) | 30 | 151 | 333 | 1333 |
Copper (Cu) | 150 | 757 | 1666 | 6666 |
Mercury (Hg) | 1 | 5 | 11 | 44 |
Molybdenum (Mo) | 4 | 20 | 44 | 177 |
Nickel (Ni) | 36 | 181 | 400 | 1600 |
Lead (Pb) | 100 | 505 | 1111 | 4444 |
Selenium (Se) | 2.8 | 14 | 31 | 124 |
Thallium (Tl) Table Note d | 1 | 5 | 11 | 44 |
Vanadium (V) Table Note d | 130 | 656 | 1444 | 5777 |
Zinc (Zn) | 370 | 1868 | 4111 | 16444 |
Table Note
- Table note d
-
Note that not all products require results of analysis for Thallium and Vanadium. These are an example of additional results that may be requested based on product or material type, on a case-by-case basis.
Note: The application rate and the metal concentration must be presented on the same basis (for example both dry weight or both as is).
Note: The Canadian Council of Ministers of the Environment (CCME), Bureau de normalisation du Québec (BNQ) and many provinces also have guidelines for metals in soils, or in sludge, compost, and other products that are land applied. We recommend that you contact your provincial government to obtain additional information.
Note that Selenium and Cobalt are considered supplemental active ingredients as they are not essential nutrients for all plant species. Including Selenium or Cobalt in a fertilizer product formulation makes the product a registrable fertilizer containing a supplement.
A compliance verification tool, an excel spreadsheet that automates metal standard calculations, is available upon request from cfia.paso-bpdpm.acia@inspection.gc.ca. It is intended to assist manufacturers/proponents and CFIA inspectors in determining conformance of the final product with the standards.
Dioxins/Furans Standard
Polychlorinated dibenzo-p-dioxins (dioxins; PCDDs) and polychlorinated dibenzofurans (furans; PCDFs) are highly persistent environmental contaminants. They are found in all living organisms at very low levels and can bioaccumulate in food chains due to their lipophilic characteristics. The CFIA standard for maximum acceptable cumulative addition to soils of dioxins and furans is 5.355 mg TEQ/ha over 45 years (where TEQ = Toxic Equivalency Quotient). Like the CFIA metals standards, the application rate of a product is a crucial element in determining acceptable product dioxins/furans concentrations and the 45 year cumulative application approach is employed to account for environmental persistence and long-term impacts. Table 6 lists the congeners to be analyzed in determining total product dioxins and furans concentration.
Compound | Toxic Equivalency Factors (TEF) | |
---|---|---|
Chlorinated dibenzo-p-dioxins | 2,3,7,8-TCDD | 1 |
Chlorinated dibenzo-p-dioxins | 1,2,3,7,8-PCDD | 1 |
Chlorinated dibenzo-p-dioxins | 1,2,3,4,7,8-HCDD | 0.1 |
Chlorinated dibenzo-p-dioxins | 1,2,3,6,7,8-HCDD | 0.1 |
Chlorinated dibenzo-p-dioxins | 1,2,3,7,8,9-HCDD | 0.1 |
Chlorinated dibenzo-p-dioxins | 1,2,3,4,6,7,8-HCDD | 0.01 |
Chlorinated dibenzo-p-dioxins | OCDD | 0.0001 |
Chlorinated dibenzofurans | 2,3,7,8-TCDF | 0.1 |
Chlorinated dibenzofurans | 1,2,3,7,8-PCDF | 0.05 |
Chlorinated dibenzofurans | 2,3,4,7,8-PCDF | 0.5 |
Chlorinated dibenzofurans | 1,2,3,4,7,8-HCDF | 0.1 |
Chlorinated dibenzofurans | 1,2,3,6,7,8-HCDF | 0.1 |
Chlorinated dibenzofurans | 1,2,3,7,8,9-HCDF | 0.1 |
Chlorinated dibenzofurans | 2,3,4,6,7,8-HCDF | 0.1 |
Chlorinated dibenzofurans | 1,2,3,4,6,7,8-HCDF | 0.01 |
Chlorinated dibenzofurans | 1,2,3,4,7,8,9-HCDF | 0.01 |
Chlorinated dibenzofurans | OCDF | 0.0001 |
Non-ortho substituted PCBs | 3,3',4,4'-PCB | 0.0001 |
Non-ortho substituted PCBs | 3,4,4',5-PCB | 0.0003 |
Non-ortho substituted PCBs | 3,3',4,4',5-PCB | 0.1 |
Non-ortho substituted PCBs | 3,3',4,4',5,5'-PCB | 0.03 |
Mono-ortho substituted PCBs | 2,3,3',4,4'-PCB | 0.00003 |
Mono-ortho substituted PCBs | 2,3,4,4',5-PCB | 0.00003 |
Mono-ortho substituted PCBs | 2,3',4,4',5-PCB | 0.00003 |
Mono-ortho substituted PCBs | 2',3,4,4',5-PCB | 0.00003 |
Mono-ortho substituted PCBs | 2,3,3',4,4',5-PCB | 0.00003 |
Mono-ortho substituted PCBs | 2,3,3',4,4',5'-PCB | 0.00003 |
Mono-ortho substituted PCBs | 2,3',4,4',5,5'-PCB | 0.00003 |
Mono-ortho substituted PCBs | 2,3,3',4,4',5,5'-PCB | 0.00003 |
The maximum acceptable product dioxins/furans concentration (in ng TEQ/kg product) is calculated using the CFIA standard for maximum acceptable 45-year cumulative dioxins/furans addition to soil (5.355mg TEQ/ha) and the product's maximum recommended annual application rate as follows:
A maximum product concentration of 100 ng TEQ/kg product is considered protective for workers and bystanders. Table 7 shows the dioxin/furan acceptable concentrations for products at different application rates.
Maximum acceptable cumulative PCDD/F additions to soil over 45 Years (mg TEQ/ha) | Examples of maximum acceptable PCDD/F concentration based on annual application rates (ng TEQ/ha) 4400 kg/ha - yr |
Examples of maximum acceptable PCDD/F concentration based on annual application rates (ng TEQ/ha) 2000 kg/ha - yr |
|
---|---|---|---|
PCDD/F | 5.355 | 27 | 59.5 |
A compliance verification tool is available from cfia.paso-bpdpm.acia@inspection.gc.ca upon request. The calculator includes functionality for persistent organic pollutants limits.
Indicator Organisms
Monitoring for microbial contaminants in fertilizers and supplements must be carried out to provide information on the adequacy of pathogen-reducing processing or sterilization steps and the microbial condition of the final product. Given their widespread presence in the environment, Salmonella and Faecal coliform density are used as indicators of microbial contamination and effectiveness of treatment process, a practice aligned with the United States Environmental Protection Agency's Part 503 Rule. The requirement of indicator organism testing allows for detection of any regrowth of bacteria and substantiates the sufficiency of pathogen reduction processes in place.
Indicator organism | Level | Minimum detection limit |
---|---|---|
Salmonella | Not Detectable | less than 1 CFU (Colony Forming Unit) / 25 grams |
Faecal Coliforms | 1000 MPN (Most Probable Number)/ gram | less than 2 CFU/gram |
Tests for indicator organisms are required to meet the minimum detection limits specified in Table 8.
A compliance verification tool is available from cfia.paso-bpdpm.acia@inspection.gc.ca upon request. The calculator includes functionality for indicator organism limits.
The CFIA reserves the right to require analyses for additional pathogenic organisms depending on the nature of the product, as assessed on a case-by-case basis.
Please refer to Health Canada's Compendium for Microbiological Analysis for examples of standard methods. To be accepted, a method must be proven to be specific, selective, reliable, and accurate for the active ingredient in the formulated products.
Upper tolerances
To promote safe use and enable compliance verification both at the premarket assessment stage as well as marketplace monitoring and enforcement, upper tolerances for micronutrient guarantees have been established. The tolerances are based on analytical variability associated with product analysis and sampling error as well as attainability based on modern manufacturing practices.
Guarantee range | Permissible guarantee exceedance |
---|---|
< 0.0033 | 0.0013 |
0.0033-0.0099 | 0.0040 |
0.010-0.032 | 0.010 |
0.033-0.099 | 0.031 |
0.10-0.32 | 0.077 |
0.33-0.99 | 0.23 |
1.0-3.2 | 0.60 |
3.3-9.99 | 1.0 |
≥ 10 | 10% of Guarantee |
For a given guarantee (left column), the permissible exceedance (numerical value) is added to the guarantee yielding the maximum allowable content (right column).
Please note that the tolerances vary depending on the range of the micronutrient guaranteed – the tolerance is greater in the low range guarantee and smaller as the concentration in the product is higher. For example, a 0.24% Cu guarantee has a permissible exceedance of 0.077, for a maximum acceptable Cu content of 0.317%. On the upper end 11% Cu guarantee has a permissible exceedance of 10% of the guarantee, in this case 1.1%, for a maximum acceptable Cu content of 12.1%.
Appendix 4: Toxicological hazards characterization
Characteristic | |
---|---|
Ingredient | |
Chemical Abstract Number (CAS#) | |
Relative Concentration in final product |
Exposure model inputs | Hazard criteria Table Note e | Value | Reference(s) |
---|---|---|---|
Organic carbon partitioning coefficient (Koc) | |||
Log Octanol Water partitioning coefficient (Log Kow) | |||
Water Solubility at 25°C | |||
Vapour Pressure | |||
Persistence Air | ≥ 2 days | ||
Persistence Water | ≥ 6 months | ||
Persistence Soil | ≥ 6 months | ||
Persistence Sediment | ≥ 1 year | ||
Bioaccumulation, Bioconcentration, Biomagnification Factors | > 5000 |
Table Note
- Table note e
-
For each ingredient where any of the hazard criteria are met, proceed to Appendix 5
Endpoint by Exposure Route | Hazard criteria Table Note f | Test organism | Term | Effect | Dose | Reference(s) |
---|---|---|---|---|---|---|
Oral Acute (LD50, NOEL, NOAEL) | LD50 ≤ 500 mg/kg bw | |||||
Oral Subchronic LO(A)EL, NO(A)EL | LO(A)EL ≤ 90 mg/kg bw | |||||
Oral Subchronic LO(A)EL, NO(A)EL | NO(A)EL ≤ 30 mg/kg bw | |||||
Oral Chronic LO(A)EL, NO(A)EL | LO(A)EL ≤ 30 mg/kg bw | |||||
Oral Chronic LO(A)EL, NO(A)EL | NO(A)EL ≤ 10 mg/kg bw | |||||
Dermal Acute (LD50, NOEL, NOAEL) | LD50 ≤ 500 mg/kg bw | |||||
Dermal Irritation/Sensitization | ||||||
Inhalation Acute (LD50, NOEL, NOAEL) | LD50 ≤ 1500 mg/m3 | |||||
Ocular Irritation | ||||||
Carcinogenicity | Indication of positive result for these endpoints triggers safety rationale | q1* | ||||
Clastogenicity and mutagenicity | Indication of positive result for these endpoints triggers safety rationale | |||||
Reproductive/Developmental Toxicity, Teratogenicity | Indication of positive result for these endpoints triggers safety rationale | |||||
Endocrine Disruption | Indication of positive result for these endpoints triggers safety rationale |
Table Note
- Table note f
-
For each ingredient where any of the hazard criteria are met, proceed to Appendix 5
q1*: cancer potency factor a measure of the relative strength of a non-threshold carcinogen.
Category | Hazard criteria Table Note g | Test organism | Term | Effect | Concn | Reference(s) |
---|---|---|---|---|---|---|
Vertebrate (for example. Rainbow trout (Oncorhynchus mykiss), Brook trout (Salvelinaus fontinalis), Fathead minnow (Pimephales promelas), Bluegill sunfish (Lepomis macrochirus)) | Acute: Lowest EC50 or LC50 < 0.1 ppm | |||||
Invertebrate (for example Daphnia (Daphnia sp., Ceriodaphnia dubia), Zebra fish (Brachydanio rerio), Worm (Lumbriculus variegatus)) | Acute: Lowest EC50 or LC50 < 0.1 ppm | |||||
Benthic (for example Amphipod (Hyallela azteca), Midge larvae (Chironomus tentans, Chironomus riparius)) | Acute: Lowest EC50 or LC50 < 0.1 ppm | |||||
Algae (for example Pseudokrchneriella subcapitata, Champia parvula) | Acute: Lowest EC50 or LC50 < 0.1 ppm |
Table Note
- Table note g
-
For each ingredient where any of the hazard criteria are met, proceed to Appendix 5
Appendix 5: Toxicological exposure and risk assessment
Only to be populated for high hazard ingredients (those that meet any of the Hazard Criteria identified in Appendix 4)
Mixer/Applicator
Assumption/Derivation/Rationale | |
---|---|
Application methodology/equipment | |
Application rate | |
Area of application (ha) | |
Frequency of application | |
Expected route(s) of exposure (for example dermal, inhalation) based on application method and product and constituent physico-chemical properties |
|
Mitigative Factors Limiting Exposure | |
Personal Protective Equipment (PPE) | |
Dermal Absorption Factor (if applicable) (% of oral dose) (DAF) | Provide value and associated reference |
Estimate of exposure, α (mg/kg bw/d) | Show derivation and associated modelling assumptions |
Assumption/Derivation/Rationale | |
---|---|
Critical endpoint and critical, β (mg/kg bw/d) and/or Cancer potency factor, q1* (mg/kg bw/d)-1 |
As identified in Appendix 4 |
Margin of Safety (β/α) and/or Incremental Lifetime Cancer Risk (ILCR) (q1* x α) |
Bystander/Indirect
Assumption/Derivation/Rationale | |
---|---|
Method of exposure (for example drift, re-entry, soil contact or consumption, potable water, plant residues) |
|
Application rate | |
Area of application | |
Frequency of exposure | |
Application setting (for example agriculture, greenhouse, residential) | |
Re-entry Interval | |
Expected route(s) of exposure (for example dermal, inhalation) based on application method and product and constituent physico-chemical properties |
|
Environmental media concentration (ppm) (as required) | Exceedance of persistence screening criteria (Appendix 4) must be accounted for in this derivation |
Estimate of exposure, α (mg/kg bw/d) | Show derivation, identify model used and associated modelling assumptions |
Assumption/Derivation/Rationale | |
---|---|
Critical endpoint dose, β (mg/kg bw/d) and/or Cancer potency factor, q1* (mg/kg bw/d)-1 |
As identified in Appendix 4 |
Margin of Safety (β/α) and/or Incremental Lifetime Cancer Risk (ILCR) (q1* x α) |
Environmental
Assumption/Derivation/Rationale | |
---|---|
Expected target environmental media (for example soil, air, aquatic, sediment) based on application method and product and constituent physico-chemical properties |
|
Application methodology/equipment | |
Application rate | |
Frequency of application | |
Environmental media concentration estimate, γ (ppm) (for example impregnated granule, soil, sediment or aquatic concentration) |
Show derivation, identify model used and associated modelling assumptions Exceedance of persistence and/or biomagnification/bioaccumulation/ bioconcentration screening criteria (Appendix 4) must be accounted for in this derivation |
Organism(s) of concern exposure estimate(s), δ (mg/kg bw/d) (if applicable, for example avian/terrestrial vertebrate toxicity) |
Show derivation, identify model used and associated assumptions (for example daily soil/granule ingestion rate) |
Assumption/Derivation/Rationale | |
---|---|
Organism(s) of concern and associated critical environmental concentration(s), ε (ppm) | As identified in Appendix 4 |
Organism(s) of concern and associated critical dose, ζ (mg/kg bw/d) (if applicable for example avian/terrestrial vertebrate toxicity) |
As identified in Appendix 4 |
Risk Quotient (ε/γ) | |
Margin of Safety (ζ/δ) (if applicable for example avian/terrestrial vertebrate toxicity) |
ε The critical effect is typically the first adverse effect that occurs with increasing dose; the critical dose is the dose at which this adverse effect is observed.
Appendix 6: Microbial hazard characterization (checklist)
Organism | Hazard | Yes/No | References |
---|---|---|---|
Human | Pathogenicity/Toxicity | ||
Human | Sensitization/Irritation | ||
Human | Dermatophytic potential | ||
Human | Toxigenicity Table Note h | ||
Mammals | Pathogenicity/Toxicity | ||
Mammals | Sensitization/Irritation | ||
Mammals | Dermatophytic potential | ||
Mammals | Toxigenicity Table Note h | ||
Other terrestrial vertebrates (for example birds) | Pathogenicity/Toxicity | ||
Other terrestrial vertebrates (for example birds) | Sensitization/Irritation | ||
Other terrestrial vertebrates (for example birds) | Toxigenicity Table Note h | ||
Terrestrial plants/crops | Pathogenicity/Toxicity | ||
Terrestrial plants/crops | Growth inhibition | ||
Terrestrial plants/crops | Post-harvest spoilage | ||
Terrestrial invertebrates (for example bees, earthworms, springtails) | Pathogenicity/Toxicity | ||
Aquatic vertebrates (fishes) | Pathogenicity/Toxicity | ||
Aquatic invertebrates (benthic, epibenthic) | Pathogenicity/Toxicity | ||
Aquatic plants (algae) | Pathogenicity/Toxicity |
Table Note
- Table note h
-
Hazard of a toxin can be estimated using established chemical models (see Appendix 4)
Hazard | Yes/No | References | |
---|---|---|---|
Microorganisms | Resistant to medically important antimicrobials Table Note i | ||
Microorganism | Contributes to environmental release of antibiotics Table Note i |
Table Note
- Table note i
-
For antimicrobial resistance, hazard is determined by classification as high priority or critical importance by the World Health Organization or Health Canada (see Appendix 11).
Appendix 7: Microbial exposure characterization - Factors to consider
Category | References |
---|---|
Geographical distribution | |
Natural habitats: soils, water, atmosphere, on or inside of living organisms (for example endophyte, epiphyte) | |
Hosts (symbiotic, saprophytic or pathogenic relationships) | |
Food/feed crops on which the microorganism is found in nature | |
Residues on food/feed (accumulation of the microorganism or its metabolites in the edible portion of the plant) Table Note j |
Table Note
- Table Note j
-
Residue data are used to estimate the dietary exposure of humans and livestock to microbial toxins.
Category | References |
---|---|
Growth parameters (for example temperature, pH, osmotic minima, maxima and optima) | |
Nutritional dependence, oxygen requirements, energy sources | |
Susceptibility to antibiotics, metals and environmental factors such as sunlight and desiccation | |
Favorable conditions for toxin production Table Note k |
Table Note
- Table Note k
-
Exposure to a toxin can be estimated using established chemical models (see Appendix 5).
Category | References |
---|---|
Characteristics of the different forms of the microorganism during its life cycle (for example motile cells, dormant cysts, spores) | |
Mechanism for reproduction and dispersal | |
Mechanism for survival (in adverse conditions) | |
Potential for dispersal of traits or gene transfer (mandatory for microorganisms modified by molecular biological techniques) |
Category | References |
---|---|
Unusual properties of the notified strain that differ from the classical description of the species (mandatory for microorganisms modified by molecular biological techniques) |
Category | References |
---|---|
Crops/plants on which the product is intended to be used | Label |
Application methodology/equipment | Label |
Application rate | Label |
Frequency of application | Label |
Expected route(s) of exposure (for example dermal, inhalation, ingestion) |
Appendix 8: Considerations for classification of microbial hazard severity and exposure level
Classification | Considerations for classification Hazard Severity |
Considerations for classification Exposure Level |
---|---|---|
High |
|
|
Medium |
|
|
Low |
|
|
Source: Adapted from Environment Canada and Health Canada (2011): Framework for Science-Based Risk Assessment of Micro-Organisms Regulated under the Canadian Environmental Protection Act, 1999
Note: Combinations of the factors within each generalized hazard severity or exposure level above are possible and would affect the overall hazard or exposure assessment.
Appendix 9: Labelling requirements for fertilizer-pesticides permitted for home and garden uses
- The headings or statements in bold type must appear on the label, but do not have to be displayed in bold type. The other statements are recommended but not required.
- Text in capital letters must be capitalized on the label unless otherwise indicated.
- The exact wording of all statements is encouraged but not mandatory as long as the meaning is the same. No contradictory information may appear on the label.
- Text in square brackets [ ] is additional information and should not be included on the label.
COMMON NAME: | CORN GLUTEN MEAL |
GUARANTEED ANALYSIS: | Corn gluten meal (actual) |
---|---|
APPROVED FOR USE: | In specialty lawn/turf fertilizers containing compatible fertilizer constituent materials. |
APPROVED CLAIMS: | Pre-emergence inhibition of large and smooth crabgrass, white clover and dandelion seed germination in residential lawns where established perennial ryegrass or established Kentucky bluegrass are the predominant grass species. Pre-emergence inhibition of large crabgrass, white clover and dandelion seed germination in public areas such as sports fields, parks, golf areas, and sod farms, where established perennial ryegrass or established Kentucky bluegrass are the predominant grass species. |
APPLICATION RATES: | 9500 - 9800 g of corn gluten meal / 100m2 |
DIRECTIONS FOR USE: | May inhibit weed seed germination when used in conjunction with a sound lawn (or turf) maintenance program. Established weeds at time of application will not be inhibited. Do not apply the product on newly seeded grass as it may inhibit seeds from germinating, wait until after first mowing when root systems are established. If over-seeding or re-sodding in the spring, do not apply the product in the spring. If over-seeding or re-sodding in the fall, do not apply the product in the fall. For best results: Apply to established turf twice a year; once in the early spring 2 weeks before weed seed germination, and once in the late summer or early fall after heat stress has passed. Apply when soil is moist and when rain is forecasted within 2 days of treatment. If rainfall does not occur within 2 days of treatment, irrigation is required. Excessive moisture at time of treatment may reduce the effectiveness of the product. Do not apply under windy conditions. Product application dates may vary for both the spring and late summer/early fall application from year to year according to weather conditions. The inhibitory effect of the product to weed seeds generally dissipates in five weeks following application. Apply to a mature lawn having a well-developed root mass. Large crabgrass seeds germinate when soil temperature reaches 12.8°C. |
PRECAUTIONS: | KEEP OUT OF REACH OF CHILDREN [on main and secondary panels]. READ THE LABEL BEFORE USING [on main panel]. CAUTION EYE IRRITANT [on main panel]. POTENTIAL SENSITIZER [on main panel]. May cause sensitization. Avoid contact with skin, eyes or clothing. Avoid inhaling dusts. For good hygiene practice, wear a long-sleeved shirt, long pants, closed footwear and gloves when handling the product. It is recommended that a dust mask be worn when transferring the product to the spreader. Should not be applied if the applicator or a member of the household has a sensitivity or allergy to corn. |
FIRST AID: | IF SWALLOWED: Rinse mouth and throat with copious amounts of water. Do not induce vomiting. IF ON SKIN/CLOTHING: Take off contaminated clothing. Wash skin with plenty of soap and water. IF INHALED: Move to fresh air. IF IN EYES: Hold eye open and rinse slowly and gently with water. Remove contact lenses if present, then continue rinsing eye. GENERAL: Seek medical attention immediately if irritation or signs of toxicity occur and persist or is severe. Take container, label or product name and registration number with you when seeking medical attention. |
TOXICOLOGICAL INFORMATION: | Treat symptomatically. |
STORAGE: | Keep in cool, dry conditions, away from seed, fertilizer and other pesticides. Keep away from fire, open flame, or other sources of heat. |
DISPOSAL: | Do not re-use empty container. Dispose in accordance with municipal or provincial regulations if applicable. If no such regulations apply, wrap and dispose of empty container with household garbage. |
NOTICE TO USER: | This product is to be used in accordance with the directions on this label. It is an offence under the Pest Control Products Act to use this product under unsafe conditions. |
ACCEPTED COMPATIBLE PESTICIDE ACTIVE INGREDIENTS: | NONE |
APPROVED BRANDS OF PESTICIDE PRODUCTS: | Refer to the corn gluten meal section PMRA’s approved brands of pesticide products |
COMMON NAME: | FERROUS SULPHATE |
GUARANTEED ANALYSIS: | Ferrous Sulphate (actual) |
---|---|
APPROVED FOR USE: | In specialty lawn/turf fertilizers containing compatible fertilizer constituent materials. |
APPROVED CLAIMS: | Controls moss in lawns. |
APPLICATION RATES: | 250 - 980 g of Ferrous sulphate / 100m2 |
DIRECTIONS FOR USE: | In lawns: Moss will take over under conditions of poor light, poor drainage and inadequate plant food. Prune trees to open up and reduce shade. Improve drainage with tiling, slit trenching or contouring. Fertilize on a regular basis. For immediate control of moss water lawn thoroughly. Spray on recommended rate. Water in to wash off grass blades; then with-hold water for several days. May also be applied at dry rate, but water in thoroughly immediately after application. |
PRECAUTIONS: | KEEP OUT OF REACH OF CHILDREN. READ LABEL BEFORE USING [on main panel]. Harmful if swallowed. Avoid contact with eyes, skin and clothing. Avoid breathing dust or spray mist. Store in its original container tightly closed and away from children and pets. Wash hands after use. May stain stone, brick masonry or light coloured sidings. May corrode bare metal. Flush off spills with clear water. Do not use on cement products such as sidewalks, patios, blocks, stucco, etc. |
FIRST AID: | IF SWALLOWED: Get medical attention or contact poison control centre. IF IN EYES: Flush with plenty of water and get medical attention or contact poison control centre. IF ON SKIN: Wash with soap and water. |
DISPOSAL: | Discard empty container in household garbage. |
ACCEPTED COMPATIBLE PESTICIDE ACTIVE INGREDIENTS: | None |
APPROVED BRANDS OF PESTICIDE PRODUCTS: | Refer to the ferrous sulphate section PMRA's approved brands of pesticide products |
Appendix 10: Information resources - Toxicology
Canadian Resources
Canadian Centre for Occupational Heal and Safety (CCOHS)
Committee on Standards, Equity, health and safety at work (CNESST)
Environment and Climate Change Canada
Health Canada
- First Priority Substances List (PSL1) Assessments
- Second Priority Substances List (PSL2) Assessments
International Resources
United Nations
- Food and Agriculture Organization (FAO), The Codex Alimentarius
- International Programme on Chemical Safety (IPCS) INCHEM
United States
- Agency for Toxic Substances and Disease Registry (ATSDR), Toxic Substances Portal
- Centers for Disease Control and Prevention (CDC), The National Institute for Occupational Safety and Health (NIOSH)
- Department of Commerce, National Institute of Standards and Technology (NIST), NIST Chemical WebBook, SRD 69
- Environmental Protection Agency (EPA), Ecotox
- Environmental Protection Agency (EPA), Integrated Risk Information System
- National Library of Medicine, Toxicological Data Network: ChemIDplus
Appendix 11: Information resources – Microbiology
Canadian departments/agencies
Canadian Food Inspection Agency (CFIA)
Environment and Climate Change Canada
- Environment Canada and Health Canada. 2011. Framework for Science-Based Risk Assessment of Micro-Organisms Regulated under the Canadian Environmental Protection Act, 1999.
- Environment Canada, Report EPS 1/RM/44. March 2004. Guidance document for testing the pathogenicity and toxicity of new microbial substances to aquatic and terrestrial organisms.
- Environment Canada, Report EPS 1/RM/46. March 2005 (with June 2007 amendments). Guidance document on statistical Methods for Environmental Toxicity Tests.
- Environment Canada. December 2013. Organisms on the Domestic Substances List (DSL) (Contains several risk group 2 microorganisms).
Health Canada/Public Health Agency of Canada
- Pathogen safety data sheets
- ePATHogen Risk Group Database
- Categorization of antimicrobial drugs based on importance in human medicine
- Canadian antimicrobial resistance surveillance system report (includes priority listing of microorganisms of concern)
International Resources
American Type Culture Collection (ATCC)
World Health Organization
OECD (Organisation for Economic Co-operation and Development)
- OECD (Organisation for Economic Co-operation and Development). 1998a. Principles of Good Laboratory Practice (as revised in 1997), No 1 - OECD Series on Principles of Good Laboratory Practice and Compliance Monitoring, ENV/MC/CHEM(98)17, 41 p., Environment Directorate, Paris, France.
- OECD (Organisation for Economic Co-operation and Development). 1999d. The application of the GLP principles to Short Term Studies, No 7 (revised) - OECD Series on Principles of Good Laboratory Practice and Compliance Monitoring, ENV/JM/MONO(99)23, 16 p., Environment Directorate, Paris, France.
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