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Piperazine dihydrochloride (PID) – Medicating Ingredient Brochure

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Status: Over the counter

Date of revision: June 2021

Table of approved species and claims
Approved livestock species Approved claim(s)
(abbreviated)Table note 1
Withdrawal time Name of approved brand(s)
Chickens
  1. Removal of large roundworms
0 days Piperazine 52
Turkeys
  1. Removal of large roundworms
0 days Piperazine 52
Swine
  1. Removal of large roundworms and nodular worms
7 days Piperazine 52

Chickens

Table of approved claims and brands
Approved claims Name of approved brand(s) Drug concentration in DIN product
Claim 1 Piperazine 52 97% piperazine dihydrochloride equivalent to 525 g/kg (52.5%) piperazine base piperazine base

Approved for use in meal or pellet feed

Claim 1

For removal of large roundworms (Ascaris) in chickens.

Level of medicating ingredient in the complete feed

1050 mg/kg (0.105%) of piperazine in the complete feed.

Directions for use in the complete feed

Feed this medicated feed as the sole ration for a 24 hour period. Treatment can be repeated in 30 days if required.

Additional information (not to appear on feed labels)

For feed manufacturers

Thoroughly mix into the feed at the following rate to provide 1050 mg/kg (0.105%) of piperazine in the complete feed:

  • 400 g (0.4 kg) of Piperazine 52 Premix with 200 kg of feed; OR
  • 2 kg of Piperazine 52 Premix with 1000 kg of feed

Warning

  1. No withdrawal period is required for chickens or chicken eggs when treated at 1050 mg/kg (0.105%) of piperazine in the complete feed.
  2. Keep out of reach of children (Required on premix and supplement labels only).

Caution

  1. Withhold feed overnight prior to medication.
  2. Provide ample hopper space.
  3. To aid in preventing re-infestation clean out the pens thoroughly shortly after medication.
  4. Good sanitation is important in controlling worm infestation.

Accepted Compatibilities

Piperazine dihydrochloride is compatible with the following drug/drug combinations. In cases where there are differences in withdrawal time for the compatible medicating ingredients, the longer withdrawal time is the one that must be used, and is the only one that is to appear on the label of the finished feed. For details, refer to the MIB as indicated.

Piperazine dihydrochloride (chickens)
Name of medicating ingredient MIB code Name of approved brand(s) Applicable claims
Penicillin G Procaine PEN Penicillin G Procaine 110 Claim 1 (broiler chickens)

Turkeys

Table of approved claims and brands
Approved claims Name of approved brand(s) Drug concentration in DIN product
Claim 1 Piperazine 52 97% piperazine dihydrochloride equivalent to 525 g/kg (52.5%) piperazine base

Approved for use in meal or pellet feed

Claim 1

For removal of large roundworms (Ascaris) in turkeys.

Level of medicating ingredient in the complete feed

2100 mg/kg (0.21%) of piperazine in the complete feed.

Directions for use in the complete feed

Feed this medicated feed as the sole ration for a 24 hour period. Treatment can be repeated in 30 days if required.

Additional information (not to appear on feed labels)

For feed manufacturers

Thoroughly mix into the feed at the following rate to provide 2100 mg/kg (0.21%) of piperazine in the complete feed:

  • 400 g (0.4 kg) of Piperazine 52 Premix with 100 kg of feed; OR
  • 4 kg of Piperazine 52 Premix with 1000 kg of feed

Warning

  1. No withdrawal period is required for turkeys when treated at 2100 mg/kg (0.21%) of piperazine in the complete feed.
  2. Keep out of reach of children (Required on premix and supplement labels only).

Caution

  1. Withhold feed overnight prior to medication.
  2. Provide ample hopper space.
  3. To aid in preventing re-infestation clean out the pens thoroughly shortly after medication.
  4. Good sanitation is important in controlling worm infestation.

Accepted Compatibilities

Nil

Swine

Table of approved claims and brands
Approved claims Name of approved brand(s) Drug concentration in DIN product
Claim 1 Piperazine 52 97% piperazine dihydrochloride equivalent to 525 g/kg (52.5%) piperazine base

Approved for use in meal or pellet feed

Claim 1

For removal of large roundworms (Ascaris suum) and nodular worms (Oesophagostomum spp.) in swine.

Level of medicating ingredient in the complete feed

3000 mg/kg (0.3%) of piperazine in the complete feed.

Directions for use in the complete feed

Feed this medicated feed as the sole ration for a 24 hour period. Treatment can be repeated in 30 days if required.

Additional information (not to appear on feed labels)

For feed manufacturers

Thoroughly mix into the feed at the following rate to provide 3000 mg/kg (0.3%) of piperazine in the complete feed:

  • 400 g (0.4 kg) of Piperazine 52 Premix with 70 kg of feed; OR
  • 1 kg of Piperazine 52 Premix with 175 kg of feed

Warning

  1. Treated swine must not be slaughtered for use in food for at least 7 days after the latest treatment with this medicated feed.
  2. Keep out of reach of children (Required on premix and supplement labels only).

Caution

  1. Withhold feed overnight prior to medication.
  2. Provide ample feeder space.
  3. To aid in preventing re-infestation clean out the pens thoroughly following medication.
  4. Good sanitation is important in controlling worm infestation.

Accepted Compatibilities

Nil