Fenbendazole (FEN) – Medicating Ingredient Brochure

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Status: Over the counter

Date of revision: May 2020

Table of approved species and claims
Approved livestock species Approved claim(s)
(abbreviated) Table Note 1
Withdrawal time Name of approved brand(s)
Swine
  1. Treatment of parasitic infections
0 days Safe-Guard
Premix 20%
Cattle
  1. Treatment of parasitic infections

13 days
(meat)

0 days
(milk)

Safe-Guard
Premix 20%
Growing turkeys
  1. Treatment of parasitic infections

1 day

Safe-Guard
Premix 20%

Swine

Table of approved claims and brands
Approved claims Name of approved brand(s) Drug concentration in DIN product
Claim 1 Safe-Guard
Premix 20%
Fenbendazole at
200 g/kg

Approved for use in mash or pellet feed

Claim 1

For the treatment of parasitic infections due to the following internal parasites in growing pigs, sows, gilts and boars:

Lung worms: Adult stage Metastrongylus apri and M. pudendotectus.

Small stomach worms: Adult stage of Hyostrongylus rubidus.

Intestinal worms: Adult and developing larval stages of the roundworm Ascaris suum, the whipworm Trichuris suis and the adult stage of the nodular worm Oesophagostomum dentatum.

Level of medicating ingredient in a complete feed

A total of 9 mg fenbendazole per kg body weight to be administered over a period of 3 to 12 days.

Directions for use in a complete feed (required to appear on feed labels)

Feed the total dose (equivalent to 9 mg fenbendazole per kg body weight) over a period of 3 to 12 days as the sole medicated feed.

Additional information (not required to appear on feed labels)

Directions for use

Thoroughly mix 125 to 500 grams of Safe-Guard Premix 20% with other feed ingredients to make one tonne of complete swine feed, as per the table below. The Safe-Guard Premix 20% must be thoroughly mixed in feeds before use.

Amount (grams) of Safe-Guard 20% premix per tonne of feed Amount of fenbendazole (mg) per kg of complete feed Treatment period Table Note 2
500 100 3 days
250 50 6 days
125 25 12 days
For feed manufacturers
  • 5 kg of premix will deworm 111 000 kg (244 900 lb) of swine

Warning

  1. No withdrawal period is required for swine when treated at the recommended dose of 9 mg fenbendazole per kg body weight over a period of 3 to 12 days
  2. When handling the product, avoid inhalation, oral exposure and direct contact with skin or eyes (required on premix and supplement labels only)
  3. Keep out of reach of children (required on premix and supplement labels only)

Caution

  1. Do not use in feed containing pellet binding agents (required on premix and supplement labels only)

Additional information to be added as notes to feed labels

Notes
  • No prior withdrawal of feed or water is necessary
  • No other medicated feed should be administered during the period of time when feed medicated with fenbendazole is fed
  • If 3 kg per 100 kg of live body weight of the pigs being treated is not sufficient to maintain the animals for 24 hours, additional non-medicated feed may be offered to appetite
  • When the above mixing and feeding directions are followed, each pig will receive 9 mg fenbendazole per kg of live body weight during the 3-12 day treatment period
  • Carefully follow the feeding directions to avoid underdosing
  • Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasites

Accepted compatibilities

Nil

Cattle

Table of approved claims and brands
Approved claims Name of approved brand(s) Drug concentration in DIN product
Claim 1 Safe-Guard
Premix 20%
Fenbendazole at
200 g/kg

Approved for use in mash or pellet feed

Claim 1

For the treatment of parasitic infections due to the following internal parasites in cattle:

Lung worms: Adult and developing 4th stage larvae of Dictyocaulus viviparus.

Stomach worms: Adult and developing 4th stage larvae of Haemonchus contortus and Ostertagia ostertagi, and the adult stage of Trichostrongylus axei.

Intestinal worms: Adult and developing 4th stage larvae of Cooperia punctata, C. oncophora, C. pectinata, C. mcmasteri, Trichostrongylus colubriformis, Nematodirus helvetianus, Bunostomum phlebotomum and Oesophagostomum radiatum.

Level of medicating ingredient in a complete feed

5 mg fenbendazole per kg body weight fed as a single dose or divided and fed over a period of one to six days.

Directions for use in a complete feed (required to appear on feed labels)

Level of the drug in the complete feed is to be such that cattle will consume a dosage of 5 mg fenbendazole per kilogram of body weight (BW) in a single dose or over a one to six day period for beef cattle, dairy heifers and dry dairy cows and administered to lactating dairy cattle as a single dose or divided and fed over a treatment period of 4 to 6 days.

Additional information (not required to appear on feed labels)

Directions for use

The required amount of Safe-Guard Premix 20% needed is determined using the following formula:

Amount of Safe-Guard Premix 20% (kg) required

=

Total animal weight (kg) × 5 mg/kg BW

÷

200 000 mg of fenbendazole per kg of Safe-Guard 20% Premix

Underdosing and / or sub-therapeutic concentrations of anthelmintic products may encourage the development of parasite resistance. It is recommended that parasite resistance be monitored following the use of any anthelmintic. There are several measures that can be implemented to help mitigate the risk of resistance, including:

  • Anthelmintics should be used in the framework of an integrated parasite control program
  • Avoid indiscriminate use of anthelmintics
  • Weigh or estimate the weight of animals as accurately as possible in order to avoid underdosing
For feed manufacturers
  • 5 kg of premix will deworm 200 000 kg (440 920 lb) of cattle
  • Safe-Guard Premix 20% must be thoroughly mixed in feeds before use

Warning

  1. Cattle treated with Safe-Guard must not be slaughtered for food use for at least 13 days after the last treatment with this drug at the recommended dose of 5 mg fenbendazole per kg body weight
  2. No milk withholding time is required when the drug is used at the recommended dose of 5 mg fenbendazole per kg body weight
  3. When handling the product, avoid inhalation, oral exposure and direct contact with skin or eyes (required on premix and supplement labels only)
  4. Keep out of reach of children (required on premix and supplement labels only)

Caution

  1. Do not use in feeds containing pellet binding agent (Required on premix and supplement labels only)

Additional information to be added as notes to feed labels

Notes
  • When the above mixing and feeding directions are followed, each animal will receive 5 mg of fenbendazole per kilogram of body weight.
  • Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasites.
  • Carefully follow the feeding directions to avoid underdosing

Accepted compatibilities

Nil

Growing turkeys

Table of approved claims and brands
Approved claims Name of approved brand(s) Drug concentration in DIN product
Claim 1 Safe-Guard
Premix 20%
Fenbendazole at
200 g/kg

Approved for use in mash or pellet feed

Claim 1

For the treatment of parasitic infections due to the following gastrointestinal parasites in growing turkeys:

Roundworms: Adults and larvae of Ascaridia dissimilis.

Cecal worms: Adults and larvae of Heterakis gallinarum.

Level of medicating ingredient in a complete feed

16 mg/kg (0.0016%) of fenbendazole in the complete feed

Directions for use in a complete feed (required to appear on feed labels)

Feed this medicated feed as the sole ration for 6 consecutive days.

Additional information (not required to appear on feed labels)

Directions for use

Underdosing and / or sub-therapeutic concentrations of anthelmintic products may encourage the development of parasite resistance. It is recommended that parasite resistance be monitored following the use of any anthelmintic. There are several measures that can be implemented to help mitigate the risk of resistance, including:

  • Anthelmintics should be used in the framework of an integrated parasite control program
  • Avoid indiscriminate use of anthelmintics
  • Weigh or estimate the weight of animals as accurately as possible in order to avoid underdosing
For feed manufacturers
  • It is recommended that Safe-Guard Premix 20% be diluted before addition to the feed. A dilution of one part of Safe-Guard Premix 20% and nine parts of grain carrier is the suggested working premix. The working premix is then blended with the complete feed mixture. Thoroughly mix both working premix and complete feed to ensure complete and uniform distribution of the Safe-Guard Premix 20%
  • The Safe-Guard Premix 20% must be thoroughly mixed in feeds before use

Warning

  1. Treated turkeys must not be slaughtered for use in food for at least 24 hours after the latest treatment with this drug
  2. When handling the product, avoid inhalation, oral exposure and direct contact with skin or eyes (required on premix and supplement labels only)
  3. Keep out of reach of children (required on premix and supplement labels only)

Caution

  1. Do not use in feed containing pellet binding agents (required on premix and supplement labels only)

Additional information to be added as notes to feed labels

Notes
  1. No prior withdrawal of feed or water is necessary
  2. Consult your veterinarian for assistance in the diagnosis, treatment, and control of parasites
  3. Carefully follow the feeding directions to avoid underdosing

Accepted compatibilities

Nil