Nicarbazin (NIC) - Medicating feed ingredient

This document is incorporated by reference into the Feeds Regulations, 2024. Any changes to this document must be made in accordance with the CFIA Incorporation by Reference Policy.

Revised December 2025

Status of medicating ingredient

Status: over the counter

Approved brands

Table of approved brands and medicating ingredient concentrations
Name of approved brand(s) Sponsor/manufacturer DIN Concentration of medicating ingredient in DIN product(s) Approved livestock species
Nicarb Feed Premix Huvepharma EOOD
5th, 3a Nikolay Haytov Street
1113 Sofia, Saone et Loire, Bulgaria
00140546 Nicarbazin at 250 g/kg Chickens
Nicarbazin 250 G Bio Agri Mix LP
11 Ellens Street
Mitchell ON
N0K 1N0
02556510 Nicarbazin at 250 g/kg Chickens

Livestock species and claims

Table of livestock species and claims

Livestock species Approved claim(s) for the medicating ingredient (abbreviated)Table note 1 Withdrawal time Name of the approved brand(s) of the medicating ingredient
Chickens

Claim 1: aid in preventing deaths from coccidiosis (mild exposure)
Claim 2: aid in preventing deaths from coccidiosis
Claim 3: aid in preventing deaths from coccidiosis in starter and grower feeds (up to 12 weeks of age)
Claim 4: aid in preventing deaths from coccidiosis in replacement chickens (8 weeks of age or over)

4 days (meat) Nicarb Feed Premix
Chickens Claim 5: aid in prevention of coccidiosis due to E. maxima in broiler chickens 2 days (meat) Nicarbazin 250 G
Table note 1

In order to be compliant with the Feeds Regulations, 2024 the complete claim must appear on the medicated feed label.

Return to footnote 1 referrer

Chickens

Claim(s)

Claim 1

As an aid in the prevention of deaths due to coccidiosis in chickens under conditions of mild exposure

Withdrawal time

4 days (meat)

Level of medicating ingredient

100 to 125 mg/kg (0.01 to 0.0125%) of nicarbazin in the complete feed

Directions for use

Feed as the sole ration

Additional information (to appear on feed labels)

Nil

Additional information (not to appear on feed labels)

Nil

Prudent use statement

Nil

Warning statement(s) (to appear on feed labels)
  • treated birds must not be slaughtered for use in food for at least 4 days after the latest treatment with this medicated feed
  • do not feed to laying or breeding hens in production
Caution statement(s) (to appear on feed labels)
  • do not use this medicated feed for the treatment of outbreaks of coccidiosis
  • if unexpected deaths occur, obtain a laboratory diagnosis and follow poultry pathologist's instructions

Claim 2

As an aid in the prevention of deaths due to coccidiosis in chickens

Withdrawal time

4 days (meat)

Level of medicating ingredient

125 to 150 mg/kg (0.0125 to 0.015%) of nicarbazin in the complete feed

Directions for use

Feed as the sole ration

Additional information (to appear on feed labels)

Nil

Additional information (not to appear on feed labels)

Nil

Prudent use statement

Nil

Warning statement(s) (to appear on feed labels)
  • treated birds must not be slaughtered for use in food for at least 4 days after the latest treatment with this medicated feed
  • do not feed to laying or breeding hens in production
Caution statement(s) (to appear on feed labels)
  • do not use this medicated feed for the treatment of outbreaks of coccidiosis
  • if unexpected deaths occur, obtain a laboratory diagnosis and follow poultry pathologist's instructions

Claim 3

In starter and grower feeds as an aid in the prevention of deaths due to coccidiosis in chickens up to 12 weeks of age

Withdrawal time

4 days (meat)

Level of medicating ingredient

200 mg/kg (0.02%) of nicarbazin in the complete feed

Directions for use

Feed as the sole ration

Additional information (to appear on feed labels)

Nil

Additional information (not to appear on feed labels)

Nil

Prudent use statement

Nil

Warning statement(s) (to appear on feed labels)
  • treated birds must not be slaughtered for use in food for at least 4 days after the latest treatment with this medicated feed
  • do not feed to laying or breeding hens in production
Caution statement(s) (to appear on feed labels)
  • do not use this medicated feed for the treatment of outbreaks of coccidiosis
  • if unexpected deaths occur, obtain a laboratory diagnosis and follow poultry pathologist's instructions

Claim 4

As an aid in preventing deaths due to coccidiosis while immunity to this disease is developing in replacement chickens 8 weeks of age or over, until birds are moved to laying house

Withdrawal time

4 days (meat)

Level of medicating ingredient

80 mg/kg (0.008%) of nicarbazin in the complete feed

Directions for use

Feed as the sole ration from 8 weeks of age or over, until birds are moved to the laying house

Additional information (to appear on feed labels)

Nil

Additional information (not to appear on feed labels)

Nil

Prudent use statement

Nil

Warning statement(s) (to appear on feed labels)
  • treated birds must not be slaughtered for use in food for at least 4 days after the latest treatment with this medicated feed chickens are slaughtered for use in food
  • do not feed to laying or breeding hens in production
Caution statement(s) (to appear on feed labels)
  • do not use this medicated feed for the treatment of outbreaks of coccidiosis
  • if unexpected deaths occur, obtain a laboratory diagnosis and follow poultry pathologist's instructions

Claim 5

As an aid in prevention of coccidiosis due to Eimeria maxima in broiler chickens

Withdrawal time

2 days (meat)

Level of medicating ingredient

125 mg/kg (0.0125%) of nicarbazin in the complete feed

Directions for use

Feed as the sole starter ration

Additional information (to appear on feed labels)

Nil

Additional information (not to appear on feed labels)

For feed manufacturers: thoroughly mix 0.5 kg of Nicarbazin 250 G per tonne of complete feed (equivalent to 125 g/tonne of active)

Feeds containing Nicarbazin 250 G are stable for up to 90 days when stored at 25 degrees Celsius and 60% relative humidity

Prudent use statement

Nil

Warning statement(s) (to appear on feed labels)
  • treated chickens must not be slaughtered for use in food for at least 2 days after the latest treatment with this drug
  • do not feed to laying hens
  • when handling Nicarbazin 250 G premix, use protective clothing, impervious gloves, and a dust mask. Avoid inhalation, oral exposure and direct contact with eyes or skin. If accidental eye or skin contact occurs, rinse thoroughly with water. If irritation occurs, seek medical attention
  • keep out of reach of children (required on premix and supplement labels only)
Caution statement(s) (to appear on feed labels)
  • do not use this medicated feed for the treatment of outbreaks of coccidiosis
  • in cases of unexpected mortality, consult a veterinarian or poultry pathologist for an exact diagnosis and follow their recommendations
  • avoid feeding this medication during periods of high heat and humidity, as nicarbazin is known to exacerbate the effects of heat stress
  • this medication should be fed in the starter ration from placement. Adverse effects may occur if nicarbazin medicated feed is started after initial placement

Accepted compatibilities

Nil