Lincomycin and Spectinomycin (LISP) – Medicating Ingredient Brochure
This page is part of the Guidance Document Repository (GDR).
Looking for related documents?
Search for related documents in the Guidance Document Repository
Status: Veterinary prescription required for approved claims
Date of revision: April 2018
|Approved livestock species||Approved claim(s)
(abbreviated)Table note 1
|Withdrawal time||Name of approved brand(s)|
||24 hours (meat)||
|Approved claims||Name of approved brand(s)||Drug concentration in DIN product|
For the prevention of swine dysentery in growing swine up to a weight of 57 kg.
Level of medicating ingredient in a complete feed
22 mg/kg (0.0022%) lincomycin and 22 mg/kg (0.0022%) spectinomycin in the complete feed.
Directions for use in a complete feed
This livestock feed contains a medically important antibiotic. To reduce the development of antimicrobial resistance and maintain effectiveness, use this antibiotic prudently and for the shortest duration required to achieve the desired clinical outcome.
Feed this medicated feed as the sole ration to growing swine up to a weight of 57 kg.
Additional information (not to appear on feed labels)
For feed manufacturers
Add and mix thoroughly into the ration at the following rate to provide 22 mg/kg (0.0022%) lincomycin and 22 mg/kg (0.0022%) spectinomycin per metric tonne (1000 kg) of finished (complete) feed:
- 1.0 kg L-S 20 Premix
- 1.0 kg Lincomycin Spectinomycin 4.4% G Premix
- Treated swine must not be slaughtered for use in food for at least 24 hours after the latest treatment with this medicated feed when fed at the recommended level of 22 mg/kg lincomycin and 22 mg/kg spectinomycin in the complete feed.
- When handling the product, avoid inhalation, oral exposure and direct contact with skin or eyes. (Required on premix and supplement labels only)
- Keep out of reach of children. (Required on premix and supplement labels only)
- Do not allow rabbits, hamsters, guinea pigs, horses, dairy cattle or other ruminants access to feeds containing lincomycin. Ingestion by these species may result in severe gastrointestinal effects or metabolic disorders (e.g. Ketosis in dairy cattle).
- Good manufacturing practices should be observed in preparing feeds containing lincomycin. This includes appropriate clean-out procedures to avoid cross contamination. (Required on premix and supplement labels only)
- Only for use in growing swine up to 57 kg bodyweight.
- Treated pigs may develop some stool softening or mild diarrhea within 36 hours of treatment initiation. Signs of mild irritation and swelling of the anus and/or vulva may be associated with the stool changes. These adverse reactions are transient and self-correcting by the fifth to eighth day of treatment. Should these reactions be more severe than described above discontinue the use of the drug.
- Feed only to swine intended for slaughter.
- Date modified: