Amprolium (AMP) – Medicating Ingredient Brochure

Status: Over the counter

Revised January 2022

Table of approved species and claims
Approved livestock species Approved claim(s) (abbreviated) Table Note 1 Withdrawal time Name of approved brand(s)
Broiler chickens
  1. Aid in prevention of deaths from coccidiosis
 0 days
  1. Amprol Feed Premix
  2. Amprolium 250
Replacement chickens
  1. Aid in the prevention of deaths from coccidiosis
  2. Aid in the prevention of deaths from light to moderate infection of coccidiosis
  3. Aid in prevention of deaths from coccidiosis
 0 days
  1. Amprol Feed Premix
  2. Amprolium 250
Turkeys
  1. Aid in the prevention of coccidiosis
 0 days
  1. Amprol Feed Premix
  2. Amprolium 250
Calves
  1. Aid in the prevention and treatment of coccidiosis caused by Eimeria bovis and Eimeria zuernii
 7 days (meat)
  1. Amprol Feed Premix
  2. Amprolium 250

Broiler chickens

Table of approved claims and brands
Approved claims Name of approved brand(s) Drug concentration in DIN product
Claim 1
  1. Amprol Feed Premix
  2. Amprolium 250
 Amprolium at 250 g/kg

Approved for use in meal or pellet feed

Claim 1

As an aid in prevention of deaths from coccidiosis in broiler chickens.

Level of medicating ingredient in the complete feed

125 or 250 mg/kg (0.0125% or 0.025%) of amprolium in the complete feed.

Directions for use in the complete feed

Feed this medicated feed as the sole ration.

Warning

  1. Do not feed to laying birds in production.

Caution

  1. Do not use amprolium medicated feeds as treatment for outbreaks of coccidiosis.
  2. If unexpected deaths occur, obtain an accurate diagnosis and follow a veterinarian's or poultry pathologist's recommendations.
  3. Do not use in feeds containing pellet binding agents except Pel-Aid and Agri-Colloid. (Required on premix and supplement labels only)

Accepted compatibilities

Amprolium is compatible with the following drug/drug combinations. In cases where there are differences in withdrawal time for the compatible medicating ingredients, the longer withdrawal time is the one that must be used, and is the only one that is to appear on the label of the finished feed. For details refer to the MIB as indicated.

Amprolium (broiler chickens)
Name of medicating ingredient MIB code Name of approved brand(s) Applicable claims
Penicillin G Procaine PEN Penicillin G Procaine 110 All claims

Replacement chickens

Table of approved claims and brands
Approved claims Name of approved brand(s) Drug concentration in DIN product
Claims 1, 2, 3
  1. Amprol Feed Premix
  2. Amprolium 250
 Amprolium at 250 g/kg

Approved for use in meal or pellet feed

Claim 1: Heavy exposure to coccidiosis

As an aid in the prevention of deaths from coccidiosis in replacement chickens intended as conventional floor managed layers.

Level of medicating ingredient in the complete feed

  1. 125 mg/kg (0.0125%) of amprolium in the complete feed to chickens aged from 0 to 5 weeks.
  2. 125 to 80 mg/kg (0.0125% to 0.008%) of amprolium in the complete feed to chickens aged from 5 to 9 weeks.
  3. 80 mg/kg (0.008%) of amprolium in the complete feed to chickens aged from 9 to 14 weeks.

Directions for use in the complete feed

Feed the appropriate level of amprolium in the medicated feed as sole ration up to 14 weeks of age as follows:

Additional information (not to appear on feed labels)

Age of chickens (weeks) Concentration of amprolium in the complete feed (mg/kg)
0-5 125
5-9 125 - 80
9-14 80

Warning

  1. Do not feed to laying birds in production.

Caution

  1. Do not use amprolium medicated feeds as treatment for outbreaks of coccidiosis.
  2. If unexpected deaths occur, obtain an accurate diagnosis and follow a veterinarian's or poultry pathologist's recommendations.
  3. Do not use in feeds containing pellet binding agents except Pel-Aid and Agri-Colloid. (Required on premix and supplement labels only)

Claim 2: Light to moderate exposure to coccidiosis

As an aid in the prevention of deaths from light to moderate infection of coccidiosis in replacement chickens intended as conventional floor managed layers.

Level of medicating ingredient in the complete feed

  1. 80 mg/kg (0.008%) of amprolium in the complete feed to chickens aged from 0 to 5 weeks.
  2. 80 to 60 mg/kg (0.008% to 0.006%) of amprolium in the complete feed to chickens aged from 5 to 9 weeks.
  3. 60 mg/kg (0.006%) of amprolium in the complete feed to chickens aged from 9 to 14 weeks.

Directions for use in the complete feed

Feed the appropriate level of amprolium in the medicated feed as sole ration up to 14 weeks of age as follows:

Additional information (not to appear on feed labels)

Age of chickens (weeks) Concertration of amprolium in the complete feed (mg/kg)
0-5 80
5-9 80 - 60
9-14 60

Warning

  1. Do not feed to laying birds in production.

Caution

  1. Do not use amprolium medicated feeds as treatment for outbreaks of coccidiosis.
  2. If unexpected deaths occur, obtain an accurate diagnosis and follow a veterinarian's or poultry pathologist's recommendations.
  3. Do not use in feeds containing pellet binding agents except Pel-Aid and Agri-Colloid. (Required on premix and supplement labels only).

Claim 3

As an aid in prevention of deaths from coccidiosis in replacement chickens intended as caged layers.

Level of medicating ingredient in the complete feed

125 or 250 mg/kg (0.0125% or 0.025%) of amprolium in the complete feed.

Directions for use in the complete feed

Feed this medicated feed from one day of age until birds are placed in cages.

Warning

  1. Do not feed to laying birds in production.

Caution

  1. Do not use amprolium medicated feeds as treatment for outbreaks of coccidiosis.
  2. If unexpected deaths occur, obtain an accurate diagnosis and follow a veterinarian's or poultry pathologist's recommendations.
  3. Do not use in feeds containing pellet binding agents except Pel-Aid and Agri-Colloid. (Required on premix and supplement labels only)

Accepted Compatibilities

Nil

Turkeys

Table of approved claims and brands
Approved claims Name of approved brand(s) Drug concentration in DIN product
Claim 1
  1. Amprol Feed Premix
  2. Amprolium 250
 Amprolium at 250 g/kg

Approved for use in meal or pellet feed

Claim 1

As an aid in the prevention of coccidiosis in turkeys.

Level of medicating ingredient in the complete feed

125 mg/kg (0.0125%) of amprolium in the complete feed.

Directions for use in the complete feed

Feed this medicated feed as the sole ration from one day of age up to and including 16 weeks of age.

Warning

  1. Do not feed to laying birds in production.

Caution

  1. Do not use amprolium medicated feeds as treatment for outbreaks of coccidiosis.
  2. If unexpected deaths occur, obtain an accurate diagnosis and follow a veterinarian's or poultry pathologist's recommendations.
  3. Do not use in feeds containing pellet binding agents except Pel-Aid and Agri-Colloid. (Required on premix and supplement labels only)

Accepted Compatibilities

Amprolium is compatible with the following drug/drug combinations. In cases where there are differences in withdrawal time for the compatible medicating ingredients, the longer withdrawal time is the one that must be used, and is the only one that is to appear on the label of the finished feed. For details refer to the MIB as indicated.

Amprolium (turkeys)
Name of medicating ingredient MIB code Name of approved brand(s) Applicable claims
Chlortetracycline hydrochloride CTC
  1. Aureomycin 220 G Granular Medicated Premix
  2. Chlor 100 Granular Medicated Premix
  3. Chlor 50 Chlortetracycline Premix
 All claims
Oxytetracycline hydrochloride OTC
  1. Terramycin – 50
  2. Terramycin – 100
  3. Terramycin – 200
  4. Oxysol-110
  5. Oxysol-220
  6. Oxysol-440
  7. Oxytetracycline 50 Granular Premix
  8. Oxytetracycline 100 Granular Premix
  9. Oxytetracycline 200 Granular Premix
 All claims

Calves

Table of approved claims and brands
Approved claims Name of approved brand(s) Drug concentration in DIN product
Claim 1
  1. Amprol Feed Premix
  2. Amprolium 250
 Amprolium at 250 g/kg

Approved for use in meal or pellet feed

Claim 1

As an aid in the prevention and treatment of coccidiosis caused by Eimeria bovis and Eimeria zuernii in calves.

Level of medicating ingredient in the complete feed

500 mg/kg (0.05%) of amprolium in the complete feed.

Directions for use in the complete feed

For prevention
Distribute this medicated feed so that each animal is supplied with 5 mg of amprolium per kg of body weight per day for 21 days during periods of exposure or when experience indicates that coccidiosis is likely to be a hazard (see Table 1 below).

For treatment
Distribute this medicated feed so that each animal is supplied with 10 mg of amprolium per kg of body weight per day for 5 days (see Table 2 below).

The tables below gives directions for using the 500 mg/kg medicated feed.

Daily intake of medicated feed (kg/head)
Table 1: 21-day preventive program
Animal weight (kg) Amount of amprolium (mg/head/day) Daily intake of medicated feed (kg/head/day)
100 500 1
200 1000 2
300 1500 3
Daily intake of medicated feed (kg/head)
Table 2: 5-day treatment program
Animal weight (kg) Amount of amprolium (mg/head/day) Daily intake of medicated feed (kg/head/day)
100 1000 2
200 2000 4
300 3000 6

Warning

  1. Treated animals must not be slaughtered for use in food for at least 7 days after the latest treatment with this drug.

Caution

  1. For a satisfactory diagnosis, a microscopic fecal examination should be done by a veterinarian or a diagnostic laboratory before treatment. When treating out breaks, the drug should be administered promptly after diagnosis.
  2. Do not feed this medicated feed to calves intended for future breeding.
  3. Do not use in feeds containing pellet binding agents except Pel-Aid and Agri-Colloid. (Required on premix and supplement labels only)

Accepted Compatibilities

Nil

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